City of Hope's National Cancer Center in Los Angeles is home to breakthrough cancer research, leading physicians and scientists, and innovative treatments that are transforming the future of cancer care. As a National Comprehensive Cancer Network® (NCCN®) Member Institution, we bring together more than 2,000 cancer experts and provide access to more than 700 clinical trials — giving patients access to the latest therapies and discoveries before they are widely available.

Our flagship National Cancer Institute (NCI)-designated comprehensive cancer center has been recognized by U.S. News & World Report as No. 1 in Southern California in the 2026-27 national cancer rankings and as one of the top hospitals for cancer care in the United States for two decades.

Whether you're seeking a second opinion or a comprehensive evaluation after a new diagnosis, you'll find expert, personalized care backed by survival outcomes that exceed national benchmarks. At City of Hope, innovation and compassionate care come together to deliver an experience — and results — that few cancer centers can match.